Invitrogen™ Human Activin R2B/ACVR2B ELISA Kit

Catalog No.	Quantity
EH8RBX5	5 x 96 Tests
EH8RB	96 Tests
EH8RBX10	10 x 96 Tests

Catalog No. EH8RBX5 Supplier Invitrogen™ Supplier No. EH8RBX5

Description

ELISA

Human Activin R2B/ACVR2B quantitates human Activin R2B/ACVR2B in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Activin R2B/ACVR2B.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

Specifications

• Accession Number: Q13705
• Assay Range: 1.3-300 ng/mL
• Assay Sensitivity: 1.3 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908;
• Gene ID (Entrez): 93
• Gene Symbol: ACVR2B
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: ACVR2B
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov