Invitrogen™ Human ALDH3A2 Synthetic Peptide

Catalog No.	Quantity
PEP0723	50 μg

Catalog No. PEP0723 Supplier Invitrogen™ Supplier No. PEP0723

Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the carboxy terminus of human Aldh3A2. PEP-0723 can be used as a blocking peptide with polyclonal antibody PA5-20603.

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

Specifications

• Gene ID (Entrez): 224
• Species: Human
• Purification Method: purified
• Accession Number: P51648
• Common Name: ALDH3A2
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; fatty aldehyde dehydrogenase; Fatty aldehyde dehydrogenase-like protein; FLJ20851; microsomal aldehyde dehydrogenase; msALDH; QccE-15682; SLS
• Gene Symbol: ALDH3A2
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS