Invitrogen™ Human ALK-6/BMPR-IB ELISA Kit

Description

ELISA

Human ALK-6/BMPR-IB quantitates human ALK-6/BMPR-IB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ALK-6/BMPR-IB.

BMPR1B (also known as ALK6, CDw293) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. BMPR1B is mainly involved in the endochondral bone formation and embryogenesis. BMPR1B expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients. BMPR1B receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation.

Specifications

• Accession Number: activin receptor-like kinase 6; Acvrlk6; AI385617; ALK6; ALK-6; AMDD; AV355320; BDA1D; BDA2; BMP type-1 B receptor; BMP15; Bmpr1b; BMPR-1 B; BMPRIB; BMPR-IB; bone morphogenetic protein binding serine/threonine kinase receptor; bone morphogenetic protein receptor IB; bone morphogenetic protein receptor type 1 B; bone morphogenetic protein receptor type IB; bone morphogenetic protein receptor type-1 B; bone morphogenetic protein receptor, type 1 B; bone morphogenetic protein receptor, type IB; CDw293; CFK-43 A; serine/threonine receptor kinase; serine/threonine-protein kinase receptor R6; SKR6
• Assay Range: 24 to 6,000 pg/mL
• Assay Sensitivity: 24 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 658
• Gene Symbol: BMPR1B
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: CDw293
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins