Invitrogen™ Human Alpha-Galactosidase A/GLA ELISA Kit

Catalog No.	Quantity
EH21RBX5	5 x 96 Tests
EH21RBX10	10 x 96 Tests
EH21RB	96 Tests

Catalog No. EH21RBX5 Supplier Invitrogen™ Supplier No. EH21RBX5

Description

ELISA

Human Alpha-Galactosidase A/GLA quantitates human Alpha-Galactosidase A/GLA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Alpha-Galactosidase A/GLA.

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Specifications

• Accession Number: P06280
• Assay Range: 45-10000 pg/mL
• Assay Sensitivity: 45 pg/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: Agalsidase; agalsidase alfa; Ags; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosidase alpha; galactosidase, alpha; GLA; MelibiaseAgalsidase; agalsidase alfa; Ags; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosidase alpha; galactosidase, alpha; GLA; Melibiase;
• Gene ID (Entrez): 2717
• Gene Symbol: GLA
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: alpha Galactosidase
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min