Invitrogen™ Human Angiostatin Native Protein

Description

Native Protein

RP-43140 contains native human Angiostatin protein. RP-43140 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: P00747
• Concentration: 4.7 mg/mL
• For Use With (Application): Control
• Formulation: 0.02 M HEPES with 0.15 M NaCl and no preservative; pH 7.4
• Gene ID (Entrez): 5340
• Molecular Weight (g/mol): 50 kDa
• Name: Human Angiostatin
• pH Range: 7.4
• Quantity: 500 μg
• Source: Human
• Regulatory Status: RUO
• Gene Alias: Activation peptide; AI649309; Angiostatin; Microplasmin; Pg; plasmin; plasmin heavy chain A; Plasmin heavy chain A, short form; Plasmin light chain B; plasminogen; PLG
• Common Name: Angiostatin
• Gene Symbol: PLG
• Conjugate: Unconjugated
• Species: Human
• Content And Storage: -20°C
• Form: Liquid
• Protein Subtype: Native

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov