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Proteintech Group Inc Human APOB ELISA Kit 96well
Supplier: Proteintech Group Inc KE0015896T
The apolipoprotein B (APOB) is a plasma protein synthesized primarily in the liver and intestine and play an important role in lipid and cholesterol metabolism. The APOB gene encodes two different isoproteins through mRNA editing, APOB-48 and APOB-100. APOB-100 is synthesized exclusively by the liver and is essential for the assembly of VLDL in the liver. APOB-48 is synthesized exclusively by the small intestine and is essential for the assembly of chylomicrons in the intestine. APOB-48 and APOB-100 share a common N-terminal sequence, but APOB-48 lacks APOB-100's C-terminal LDL receptor binding region. Plasma APOB levels are associated with coronary heart disease.
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