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Abnova™ Human APOE native Protein from human plasma

Used for SDS-PAGE

Manufacturer:  Abnova™ P4281

Catalog No. 89-935-359


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Description

Description

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq]

Specifications

Specifications

Native protein purified from human plasma
Liquid
348
APOE (Human) Native Protein
≥95% by SDS-PAGE
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
AD2/LPG/MGC1571/apoprotein
APOE
None
Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
In 50mM NH
34kDa
Native protein purified from human plasma
50 ug
RUO
APOE
Human
SDS
Documents
Product Certifications
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