Abnova™ Human APOE native Protein from human plasma

Catalog No.	Quantity
89-935-359	50 μg

Catalog No. 89-935-359 Supplier Abnova™ Supplier No. P4281

Description

Used for SDS-PAGE

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq]

Specifications

• For Use With (Application): SDS-PAGE
• Formulation: In 50mM NH
• Gene ID (Entrez): 348
• Molecular Weight (g/mol): 34kDa
• Name: APOE (Human) Native Protein
• Preparation Method: Native protein purified from human plasma
• Quantity: 50 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: AD2/LPG/MGC1571/apoprotein
• Common Name: APOE
• Gene Symbol: APOE
• Species: Human
• Protein Tag: None
• Expression System: Native protein purified from human plasma
• Form: Liquid
• Purity or Quality Grade: ≥95% by SDS-PAGE