Invitrogen™ Human ARHGAP18 Synthetic Peptide

Catalog No.	Quantity
PEP1007	50 μg

Catalog No. PEP1007 Supplier Invitrogen™ Supplier No. PEP1007

Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human ARHGAP18. PEP-1007 can be used as a blocking peptide with polyclonal antibody PA5-20893.

ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.

Specifications

• Gene ID (Entrez): 93663
• Species: Human
• Purification Method: purified
• Accession Number: Q8N392
• Common Name: ARHGAP18
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; MacGAP; Rho GTPase activating protein 18; rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX
• Gene Symbol: ARHGAP18
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS