Invitrogen™ Human Artemin ELISA Kit

ELISA

Supplier:  Invitrogen™ EH37RBX5

Catalog No. EH37RBX5

Description

Human Artemin quantitates human Artemin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Artemin.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
• Assay Sensitivity: 4 pg/mL
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene Symbol: ARTN
• Intraassay CV: <10
• Label or Dye: HRP
• Regulatory Status: RUO
• Storage Requirements: 2°C to 8°C
• Test Time: 1 hrs 20 mins

• Assay Range: 4.10 to 1,000 pg/mL
• Conjugate: HRP
• Sample Type: Plasma, Serum, Supernatant
• Gene ID (Entrez): 9048
• Interassay CV: <12%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Quantity: 5 x 96 Tests
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Target: Artemin
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

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