Invitrogen™ Human ATP6V1G2 (aa 68-104) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP109164	100 μL

Catalog No. RP109164 Supplier Invitrogen™ Supplier No. RP109164

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140243. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene.

Specifications

• Accession Number: O95670
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 534
• Name: Human ATP6V1G2 (aa 68-104) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 1500002D01Rik; ATP6G; Atp6g2; ATP6V1G1; Atp6v1g2; ATPase H+ transporting V1 subunit G2; ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATPase, H+ transporting, lysosomal 13kD, V1 subunit G; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; ATPase, H+ transporting, lysosomal V1 subunit G2; ATPase, H+ transporting, V1 subunit G; H(+)-transporting two-sector ATPase, subunit G2; LOC514368 protein; lysosomal 13kDa; NG38; vacuolar ATP synthase subunit G 2; vacuolar ATPase NG38; vacuolar proton pump G subunit 2; vacuolar proton pump subunit G 1; Vacuolar proton pump subunit G 2; VAG2; V-ATPase 13 kDa subunit 2; V-ATPase subunit G 1; V-ATPase subunit G 2; VMA10; V-type proton ATPase subunit G 1; V-type proton ATPase subunit G 2
• Common Name: ATP6V1G2
• Gene Symbol: ATP6V1G2
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: NLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVC
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining