Invitrogen™ Human AZGP1 (aa 24-145) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP100376	100 μL

Catalog No. RP100376 Supplier Invitrogen™ Supplier No. RP100376

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52951. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.

Specifications

• Accession Number: P25311
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 563
• Name: Human AZGP1 (aa 24-145) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: alpha-2 - glycoprotein 1 zinc; alpha-2 - glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc-binding; Alpha-2-glycoprotein, zinc; Azgp1; major histocompatibility complex class I-like protein; testicular tissue protein Li 227; ZA2G; ZA2GA; Zag; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; zinc alpha-2-glycoprotein 1; Zinc α 2 glycoprotein; Zinc α2glycoprotein; zinc-alpha-2-glycoprotein; Zn - alpha2 - glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; Zna2gp; zn-alpha-2-glycoprotein; Zn-alpha2-glycoprotein; zn-alpha-2-GP; ZNGP1
• Common Name: AZGP1
• Gene Symbol: AZGP1
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: QDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining