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Invitrogen™ Human Bestrophin 4 (aa 252-286) Control Fragment Recombinant Protein

Catalog No. RP101335
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RP101335 100 μL
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Catalog No. RP101335 Supplier Invitrogen™ Supplier No. RP101335
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (39%), Rat (39%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63587. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8NFU0
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 266675
Name Human Bestrophin 4 (aa 252-286) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias BEST4; bestrophin 4; bestrophin-4; si:ch211-106k21.4; similar to vitelliform macular dystrophy 2-like 2; vitelliform macular dystrophy 2-like 2; vitelliform macular dystrophy 2-like protein 2; VMD2L2
Common Name Bestrophin 4
Gene Symbol BEST4
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDM
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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