Gibco™ Human beta-Defensin 1 Recombinant Protein

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Specifications

• Accession Number: P60022
• For Use With (Application): Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
• Formulation: 10 mM acetic acid with no preservative
• Gene ID (Entrez): 1672
• Molecular Weight (g/mol): 3.9 kDa
• Name: Human beta-Defensin 1
• Purification Method: Sequential Chromatography
• Quantity: 20 μg
• Endotoxin Concentration: <0.1 ng/ μg
• Gene Alias: AW260221; BD1; BD-1; beta defensin 1; beta-defensin 1; beta-defensin-1; DEFB1; DEFB-1; DEFB101; defensin beta 1; defensin, beta 1; HBD1; rBD-1
• Common Name: beta-Defensin 1
• Biological Activity: ED50 = 100 - 1000 ng/mL; determined by the dose-dependent chemotaxis of of human CD34+ dendritic cells.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human beta-Defensin 1 recombinant protein contains 36 amino acids
• Content And Storage: -20°C
• Classification: Carrier-Free
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Approved for shipment on Wet or Dry Ice
• Expression System: E. coli
• Protein Family: Cytokines & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: Other Proteins
• Research Category: Immunology
• Product Line: Gibco™
• Purity or Quality Grade: ≥98% by SDS-PAGE and HPLC