Invitrogen™ Human C1qTNF5 ELISA Kit

Catalog No.	Quantity
EH54RBX5	5 x 96 Tests
EH54RBX10	10 x 96 Tests
EH54RB	96 Tests

Catalog No. EH54RBX5 Supplier Invitrogen™ Supplier No. EH54RBX5

Description

ELISA

Human C1qTNF5 quantitates human C1qTNF5 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human C1qTNF5.

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

Specifications

• Accession Number: Q9BXJ0
• Assay Range: 0.82-200 ng/mL
• Assay Sensitivity: 0.82 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: C1q and tumor necrosis factor related protein 5; C1q TNF-alpha-related protein 5; C1qtnf5; Complement C1q tumor necrosis factor-related protein 5; Ctrp5; LORD; Membrane frizzled-related protein; Membrane-type frizzled-related protein; Mfrp; myonectin; UNQ303/PRO344C1q and tumor necrosis factor related protein 5; C1q TNF-alpha-related protein 5; C1qtnf5; Complement C1q tumor necrosis factor-related protein 5; Ctrp5; LORD; Membrane frizzled-related protein; Membrane-type frizzled-related protein; Mfrp; myonectin; UNQ303/PRO344;
• Gene ID (Entrez): 114902
• Gene Symbol: C1QTNF5
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: CTRP5
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min