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Invitrogen™ Human CBX8 Control Fragment Recombinant Protein

Catalog No. RP102525
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RP102525 100 μL
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Catalog No. RP102525 Supplier Invitrogen™ Supplier No. RP102525
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83193. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9HC52
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 57332
Name Human CBX8 Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias CBX8; chromobox 8; chromobox homolog 8; chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; HPC3; mPc3; Pc class 3 homolog; Pc3; polycomb 3; polycomb 3 homolog; RC1; rectachrome 1
Common Name CBX8
Gene Symbol CBX8
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSVGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGF
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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