Gibco™ Human CCL20 (MIP-3 alpha) Recombinant Protein

Catalog No.	Quantity
PHC1234	20 μg

Catalog No. PHC1234 Supplier Gibco™ Supplier No. PHC1234

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute recombinant human MIP-3 alpha in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.

Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.

Specifications

• Accession Number: P78556
• For Use With (Application): Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 6364
• Molecular Weight (g/mol): 8 kDa
• Name: Human CCL20 (MIP-3 alpha)
• Purification Method: Purified
• Quantity: 20 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: beta chemokine exodus-1; beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; LARC; Liver and activation-regulated chemokine; macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 α; MIP 3alpha; MIP 3α; MIP3 a; MIP3 alpha; MIP3 α; MIP-3[a]; MIP3A; MIP-3A; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; small-inducible cytokine A20; St38
• Common Name: CCL20
• Gene Symbol: CCL20
• Biological Activity: ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human CCL20 recombinant protein contains 70 amino acids
• Content And Storage: -20°C
• Classification: Carrier-Free
• Activity: ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Wet Ice
• Expression System: E. coli
• Protein Family: Chemokines & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: MIP (Macrophage Inflammatory Protein) Chemokines
• Research Category: Immunology, Inflammation, Signal Transduction, Neurobiology
• Product Line: Gibco
• Purity or Quality Grade: >98% by SDS-PAGE