Gibco™ Human CCL21 (6Ckine) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Supplier:  Gibco™ 30035A50UG

Catalog No. 30035A50UG

Description

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Specifications

• Accession Number: O00585
• Format: Lyophilized
• Gene ID (Entrez): 6366
• Name: Human CCL21 (6 Ckine)
• Quantity: 50 µg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/µg
• Gene Symbol: CCL21
• Conjugate: Unlabeled
• Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P

• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 12.2
• Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: 6 Ckine; 6 CKBAC1; 6 CKBAC2; 6 Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6 Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21 A; C-C motif chemokine 21 b; C-C motif chemokine 21 c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21 A (serine); chemokine (C-C motif) ligand 21 B (leucine); chemokine (C-C motif) ligand 21 b (serine); chemokine (C-C motif) ligand 21 C (leucine); chemokine CCL21/6 CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600
• Specific Reactivity: Human
• Recombinant: Yes