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ACROBiosystems Human CCL3, His Tag (CC3-H5249) is expressed from E.coli cells. It contains AA Ser 24 - Ala 92 (Accession # P10147-1).
Supplier: ACROBiosystems CC3H524950UG
CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
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