This product consists of full-length human CD133 (Prominin-1) protein presented as virus-like particles (VLPs). CD133 is a pentaspan membrane glycoprotein that serves as a marker for cancer stem cells in various malignancies, including glioblastoma, colorectal, and liver cancers. The protein is expressed in human 293 cells (HEK293) and incorporates transmembrane proteins into a lipid bilayer, preserving authentic conformation, post-translational modifications, and orientation in a detergent-free environment.
- Greater than 95% purity as determined by SEC-HPLC
- Contains amino acids Gly 20 to His 865
- Endotoxin level is less than 1.0 EU per μg
- Suitable for immunization, ELISA screening, and cell-based assays like FACS
- Supplied as a 0.2 μm filtered solution in PBS, pH 7.4, with trehalose