Invitrogen™ Human CD155 (PVR) Fc Chimera Recombinant Protein

Catalog No.	Quantity
PIRP87969	1 mg
PIRP87968	100 μg

Catalog No. PIRP87969 Supplier Invitrogen™ Supplier No. RP87969

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1205 μL) be added to the vial to prepare a stock solution of 0.83 mg/mL. Concentration is measured by UV.

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: P15151
• For Use With (Application): Control, ELISA Standard, Binding Assay
• Format: Lyophilized
• Formulation: PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
• Gene ID (Entrez): 5817
• Molecular Weight (g/mol): 61.8 kDa
• Name: Human CD155 (PVR) Fc Chimera
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: 3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
• Common Name: CD155
• Gene Symbol: PVR
• Biological Activity: 1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 His at 2 μg/mL (100 μL/well) can bind human CD155 hFc, The EC50 of bind human CD155 hFc is 100-800 ng/mL 2. Immobilized TIGIT Protein, Human, Recombinant (ECD, His Tag) (at 2 μg/ml (100 μL/well) can bind CD155/PVR Protein, Human, Recombinant (ECD, hFc Tag), the EC50 of CD155/PVR Protein, Human, Recombinant (ECD, hFc Tag) is 25-140 ng/mL)
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: Human CD155, amino acids Met1-Asn343 (Accession # P15151-1) with a C-terminal human IgG1 Fc region
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Activity: ELISA Activity: Immobilized Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat: 10917-H08H3) at 2ug/mL (100uL/well) can bind Recombinant Human CD155/PVR/NECL5 Protein (Fc Tag) (Cat: 10109--H02H), the EC50 is 10-30ng/mL
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95 % as determined by SDS-PAGE