Invitrogen™ Human CD27L (TNFSF7) Fc Chimera Recombinant Protein

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (450 μL) be added to the vial to prepare a stock solution of 2.22 mg/mL. Concentration is measured by UV.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Specifications

• Accession Number: P32970
• For Use With (Application): ELISA
• Format: Lyophilized
• Formulation: PBS with 0.01% mannitol, 0.01% Tween 80, 5-8% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 970
• Molecular Weight (g/mol): 45.5 kDa
• Name: Human CD27L (TNFSF7) Fc Chimera
• Purification Method: SDS-PAGE
• Quantity: 1 mg
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8 A; tumor necrosis factor ligand superfamily member 7
• Common Name: CD70
• Gene Symbol: Cd70
• Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His (at 2 μg/ml (100 μL/well) can bind Human CD70 hFc, the EC50 of Human CD70 hFc is 15-60 ng/mL)
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: Human CD27L, amino acids Gln39-Pro193 (Accession # NP_001243.1) with an N-terminal human IgG1 Fc region
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His (at 2 μg/ml (100 μL/well) can bind Human CD70 hFc, the EC50 of Human CD70 hFc is 15-60 ng/mL)
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >90% as determined by SDS-PAGE.