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ACROBiosystems Human CD47 96tests

Catalog No. 502535101
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CD47 is a transmembrane protein a cell surface glycoprotein molecule belonging to the immunoglobulin superfamily that binds to a variety of proteins including integrins thrombospondin 1 and signal regulatory protein-α (SIRPα). In recent years accumulating data have demonstrated that the CD47-SIRPαV2 axis is a key immune checkpoint in different cancers including hematological malignancies similar to PD-1/PD-L1 in solid tumors. CD47-SIRPαV2 blockade has become a next-generation immune checkpoint blocking strategy for various malignancies after PD-1/PD-L1.

Catalog No. 50-253-5101 Supplier ACROBiosystems Supplier No. EP16096TESTS
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CD47 is a transmembrane protein a cell surface glycoprotein molecule belonging to the immunoglobulin superfamily that binds to a variety of proteins including integrins thrombospondin 1 and signal regulatory protein-α (SIRPα). In recent years accumulating data have demonstrated that the CD47-SIRPαV2 axis is a key immune checkpoint in different cancers including hematological malignancies similar to PD-1/PD-L1 in solid tumors. CD47-SIRPαV2 blockade has become a next-generation immune checkpoint blocking strategy for various malignancies after PD-1/PD-L1.

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