Invitrogen™ Human CETP (aa 149-159) Synthetic Peptide

Catalog No.	Quantity
PEP209	50 μg

Catalog No. PEP209 Supplier Invitrogen™ Supplier No. PEP209

Description

Synthetic Peptide

PEP-209 is a 12 amino acid synthetic peptide. The sequence of this peptide is (amino to carboxy terminus: C D (149) S G R V R T D A P D (159). This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog # PA1-050. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water.

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Specifications

• Gene ID (Entrez): 1071
• Species: Human
• Purification Method: purified
• Accession Number: P11597
• Common Name: CETP
• Concentration: 0.5 mg/mL
• Content And Storage: -20°C. Avoid freeze-thaw cycles.
• Description: Synthetic Peptide
• Format: Lyophilized
• Formulation: Peptide with no preservative
• For Use With (Application): Control
• Gene Alias: BPI fold containing family F; BPIFF; CETP; Cholesteryl ester transfer protein; cholesteryl ester transfer protein plasma; cholesteryl ester transfer protein, plasma; HDLCQ10; Lipid transfer protein I
• Gene Symbol: CETP
• Lyophilized: Yes
• Preservative: No preservative
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Sequence: C D(149) S G R V R T D A P D(159)