Gibco™ Human CHI3L1 Recombinant Protein, PeproTech®

Catalog No.	Quantity
50-003-31931	100 μg
45-065-1MG	1 mg
50-003-31932	250 μg
50-003-31933	500 μg
45-065-50UG	50 μg

Catalog No. 50-003-31931 Supplier Gibco™ Supplier No. 45065100UG

Description

Recombinant Protein

Recombinant Human Chitinase-3-like protein 1 (CGP39) is a 40.5 kDa monomeric protein containing 362 amino-acid resideus comprised of the mature sequence of the protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis.

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

Specifications

• Accession Number: P36222
• For Use With (Application): Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 1116
• Molecular Weight (g/mol): 40.5 kDa
• Name: Human CHI3L1
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/μg
• Gene Alias: 38 kDa heparin-binding glycoprotein; 38kDa heparin-binding glycoprotein; 39 kDa synovial protein; 39 kDa whey protein; 40 kDa secretory signalling glycoprotein; ASRT7; AW208766; BP40; BP40 precursor; breast regression protein 39; Brp39; BRP39 protein; Cartilage glycoprotein 39; cartilage glycoprotein-39; CGP39; CGP-39; CHI3L1; Chil1; chitinase 3 like 1; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase 3-like 1 protein; chitinase-3-like protein 1; chitinase-like 1; chitinase-like protein 1; CLP-1; DKFZp686N19119; FLJ38139; GP38K; Gp39; GP-39; hCGP39; HC-gp39; hCGP-39; HCGP-3P; Mammary gland protein 40; MGP-40; signal processing protein; signal-processing protein; SPC-40; SPS-40; YKL40; YKL-40; YYL-40
• Common Name: CHI3L1
• Gene Symbol: CHI3L1
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: YKLVCYYTSW SQYREGDGSC FPDALDRFLC THIIYSFANI SNDHIDTWEW NDVTLYGMLN TLKNRNPNLK TLLSVGGWNF GSQRFSKIAS NTQSRRTFIK SVPPFLRTHG FDGLDLAWLY PGRRDKQHFT TLIKEMKAEF IKEAQPGKKQ LLLSAALSAG KVTIDSSYDI AKISQHLDFI SIMTYDFHGA WRGTTGHHSP LFRGQEDASP DRFSNTDYAV GYMLRLGAPA SKLVMGIPTF GRSFTLASSE TGVGAPISGP GIPGRFTKEA GTLAYYEICD FLRGATVHRI LGQQVPYATK GNQWVGYDDQ ESVKSKVQYL KDRQLAGAMV WALDLDDFQG SFCGQDLRFP LTNAIKDALA AT
• Activity: Determined by its ability to support adhesion of Human FaDu cells.
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.