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Sino Biological Recombinant Human Claudin-4/CLDN4 Protein (Detergent, Full-length, Flag Tag)
Supplier: Sino Biological 16358H25HDD100
A DNA sequence encoding the Human CLDN4-Detergent (Full Length) (O14493) (Met1-Val209) was fused with a flag tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our detergent platform. The transmembrane proteins' hydrophobic regions pose a challenge in maintaining their native conformation post-extraction from cellular membranes in standard buffers. To address this, our detergent technology platform utilizes a traditional yet proven membrane protein extraction method, incorporating detergents to stabilize the proteins. This method efficiently produces highly purified membrane protein products, suitable for use in early drug screening and research applications.
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