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Invitrogen™ Human Cluster of Differentiation 6/CD6 ELISA Kit
Description
Human Cluster of Differentiation 6/CD6 quantitates human Cluster of Differentiation 6/CD6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cluster of Differentiation 6/CD6.
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
Specifications
Specifications
| Accession Number | P30203 |
| Assay Range | 0.23-50 ng/mL |
| Assay Sensitivity | 0.23 ng/mL |
| Conjugate | HRP |
| Immunoassay Kit Format | Sandwich ELISA Kit |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| Target Species | Human |
| For Use With (Equipment) | Absorbance Microplate Reader |
| Gene Alias | Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120; |
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