Invitrogen™ Human COCO ELISA Kit

Description

ELISA

Human COCO quantitates human COCO in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human COCO.

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Specifications

• Accession Number: CER2; CER2CRL2; cerberus 2; Cerberus like-2; cerberus-like 2; cerberus-like protein 2; CERL2; Cerl-2; Cerr2; CKTSF1B3; CKTSF1B3MGC126849; COCO; CRL2; Cysteine knot superfamily 1, BMP antagonist 3; DAN domain BMP antagonist family member 5; DAN domain family member 5; DAN domain family member 5, BMP antagonist; DAN domain family, member 5; DAND5; DANTE; Dte; FLJ38607; GREM3; GREM3cerberus 2; Gremlin-3; MGC126849; SP1
• Assay Range: 0.2 to 50 ng/mL
• Assay Sensitivity: 0.2 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 199699
• Gene Symbol: DAND5
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: DAND5
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov