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  5. Invitrogen™ Human CRIM1 ELISA Kit 

Invitrogen™ Human CRIM1 ELISA Kit

Catalog No. EH129RBX5
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EH129RB 96 Tests
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Description

ELISA

Human CRIM1 quantitates human CRIM1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRIM1.

CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number AU015004; Crim1; CRIM-1; cysteine rich transmembrane BMP regulator 1; cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine rich transmembrane BMP regulator 1 (chordin-like); cysteine-rich motor neuron 1; cysteine-rich motor neuron 1 protein; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1 protein; S52; UNQ1886/PRO4330
Assay Range 0.041 to 10 ng/mL
Assay Sensitivity 0.041 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 51232
Gene Symbol CRIM1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target CRIM1
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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