Invitrogen™ Human CRTAM ELISA Kit

Catalog No.	Quantity
EH134RBX5	5 x 96 Tests
EH134RB	96 Tests

Catalog No. EH134RBX5 Supplier Invitrogen™ Supplier No. EH134RBX5

Description

ELISA

Human CRTAM quantitates human CRTAM in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRTAM.

Class-I MHC-restricted T cell-associated molecule (CRTAM) is a gene located on chromosome 11q24.2, encoding a member of the immunoglobulin superfamily that plays a crucial role in immune cell interactions. CRTAM is expressed on activated CD8+ T cells, natural killer (NK) cells, and some subsets of CD4+ T cells, where it is involved in promoting cell adhesion, cytokine production, and cytotoxic responses. The protein binds to Necl-2 (CD112), mediating intercellular communication that influences immune responses, particularly in the context of viral infections and tumor surveillance. CRTAM's involvement in directing immune cell activity highlights its importance in the regulation of adaptive and innate immunity. Research into CRTAM is exploring its potential as a therapeutic target for modulating immune functions, aiming to enhance immune responses against cancer and infectious diseases or to attenuate autoimmune reactions.

Specifications

• Accession Number: O95727
• Assay Range: 0.6-150 ng/mL
• Assay Sensitivity: 0.6 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: CD355; CD355 antigen; class I MHC restricted T cell associated molecule; class I-restricted T cell-associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; Crtam; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell moleculeCD355; CD355 antigen; class I MHC restricted T cell associated molecule; class I-restricted T cell-associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; Crtam; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule;
• Gene ID (Entrez): 56253
• Gene Symbol: CRTAM
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: CRTAM
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov