Invitrogen™ Human CT47 (aa 246-273) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP104338	100 μL

Catalog No. RP104338 Supplier Invitrogen™ Supplier No. RP104338

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (54%), Rat (54%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59991. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CT47 (cancer/testis antigen family 47) is a 288 amino acid protein that is strongly expressed in testis and lowly expressed in placenta and in brain. The gene encoding CT47 is located on human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Specifications

• Accession Number: Q5JQC4
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 728096
• Name: Human CT47 (aa 246-273) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: Cancer/testis antigen 47; Cancer/testis antigen 47A; cancer/testis antigen family 47, member A1; cancer/testis CT47 family, member 1; CT47; CT47.1; CT47.10; CT47.11; CT47.12; CT47.2; CT47.3; CT47.4; CT47.5; CT47.6; CT47.7; CT47.8; CT47.9; CT47A; CT47A1; CT47A10; CT47A11; CT47A12; CT47A2; CT47A3; CT47A4; CT47A5; CT47A6; CT47A7; CT47A8; CT47A9
• Common Name: CT47
• Gene Symbol: CT47A1
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PEEVTKSQPEKWDEEAQDAAGEEEKEQE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining