Invitrogen™ Human CTX-II ELISA Kit

Description

ELISA

CTX-II is a biomarker for type II collagen degradation, which is mainly found in cartilage. It is a small peptide fragment that is released into the synovial fluid and blood when there is cartilage degradation. CTX-II has been extensively studied as a diagnostic and prognostic marker for osteoarthritis, and it has also been shown to be a useful tool for monitoring the efficacy of treatments targeting cartilage degradation. The structure of CTX-II is a small peptide consisting of 17 amino acids. It is derived from the C-terminal telopeptide of type II collagen. CTX-II functions as a biomarker for cartilage degradation and can be used to monitor the progression of osteoarthritis and the effectiveness of treatments.

Specifications

• Assay Range: 0.16 to 10 ng/mL
• Assay Sensitivity: 0.1 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum
• For Use With (Equipment): Colorimetric Microplate Reader
• Interassay CV: <10%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
• Label or Dye: HRP
• Quantity: 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 100 μL, Serum 100 μL
• Storage Requirements: Refer to product documentation for component specific storage temperature.
• Target: CTX-II
• Test Time: 1 hrs 20 mins
• Total Assay Time: 3 hrs 30 mins