Invitrogen™ Human CXCL4 (PF4) Native Protein

Description

Native Protein

RP-43149 contains native human Platelet Factor 4 protein. RP-43149 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).

Specifications

• Accession Number: P02776
• Concentration: 0.74 mg/mL
• For Use With (Application): Control
• Formulation: 0.025 M HEPES with 2 M NaCl and no preservative; pH 7.4
• Gene ID (Entrez): 5196
• Molecular Weight (g/mol): 29 kDa
• Name: Human CXCL4 (PF4)
• pH Range: 7.4
• Quantity: 100 μg
• Source: Human
• Regulatory Status: RUO
• Gene Alias: chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; Cxcl4; Endothelial cell growth inhibitor; Iroplact; oncostatin-A; PF4; PF-4; Pf4a; Platelet factor 4; Platelet factor 4, short form; RATPF4A; Scyb4
• Common Name: PF4
• Gene Symbol: PF4
• Conjugate: Unconjugated
• Species: Human
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Protein Subtype: Native

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov