Invitrogen™ Human DAD1 Synthetic Peptide

Catalog No.	Quantity
PEP0181	50 μg

Catalog No. PEP0181 Supplier Invitrogen™ Supplier No. PEP0181

Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the amino terminus of human DAD1. PEP-0181 can be used as a blocking peptide with polyclonal antibody PA5-20062.

Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death, a process important for normal organism development and tissue homeostasis. DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity. Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death. Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas, indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Specifications

• Gene ID (Entrez): 1603
• Species: Human
• Purification Method: purified
• Accession Number: P61803
• Common Name: DAD1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: AI323713; Dad1; DAD-1; Defender against cell death 1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Oligosaccharyl transferase subunit DAD1; oligosaccharyltransferase 2 homolog; oligosaccharyltransferase subunit 2 (non-catalytic); OST2
• Gene Symbol: DAD1
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov