Invitrogen™ Human DCLK3 Synthetic Peptide

Catalog No.	Quantity
PEP1025	50 μg

Catalog No. PEP1025 Supplier Invitrogen™ Supplier No. PEP1025

Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the carboxy terminus of human DCLK3. PEP-1025 can be used as a blocking peptide with polyclonal antibody PA5-20911.

DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.

Specifications

• Gene ID (Entrez): 85443
• Species: Human
• Purification Method: purified
• Accession Number: Q9C098
• Common Name: DCLK3
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: BC056929; C730036H08; CLICK-I and II-related; Click-I, -II related; CLICK-I,II-related; CLR; Dcamkl3; DCDC3C; DCK3; Dclk3; doublecortin and CaM kinase-like 3; doublecortin domain-containing protein 3C; doublecortin like kinase 3; doublecortin-like and CAM kinase-like 3; Doublecortin-like kinase 3; hCG_16695; KIAA1765; RGD1309232; serine/threonine-protein kinase DCLK3
• Gene Symbol: DCLK3
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS