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Invitrogen™ Human DTX4 (aa 241-326) Control Fragment Recombinant Protein

Catalog No. RP97284
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RP97284 100 μL
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Catalog No. RP97284 Supplier Invitrogen™ Supplier No. RP97284
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63699. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9Y2E6
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 23220
Name Human DTX4 (aa 241-326) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AI449438; BC044798; D930042H13; deltex 4 homolog; deltex 4 homolog (Drosophila); deltex 4, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 4; deltex homolog 4; deltex4; DTX4; E3 ubiquitin-protein ligase DTX4; KIAA0937; LRRGT00037; Protein deltex-4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4; RNF155
Common Name DTX4
Gene Symbol DTX4
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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