Abnova™ Human EGFR (NP_005219.2, 669 a.a. - 1210 a.a.) L861Q mutant parial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Catalog No.	Quantity
89-942-930	5 μg

Catalog No. 89-942-930 Supplier Abnova™ Supplier No. P5700

Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]

Specifications

• Accession Number: NP_005219.2
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 1956
• Molecular Weight (g/mol): 89kDa
• Name: EGFR (L861Q) (Human) Recombinant Protein
• Preparation Method: Baculovirus expression system
• Purification Method: Glutathione sepharose chromatography
• Quality Control Testing: Loading 1 ug protein in SDS-PAGE
• Quantity: 5 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: ERBB/ERBB1/HER1/PIG61/mENA
• Common Name: EGFR
• Gene Symbol: EGFR
• Biological Activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
  Substrate : Srctide. ATP: 100 μM.
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST
• Expression System: Baculovirus expression system
• Form: Liquid
• Purity or Quality Grade: 86% by SDS-PAGE/CBB staining.