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Sigma Aldrich Fine Chemicals Biosciences Human Epidermal Melanocyte
Supplier: Sigma Aldrich Fine Chemicals Biosciences 10405A

Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis where they interact with keratinocytes via cellular processes called dendrites. Melanin the pigment produced by melanocytes and responsible for skin color is then transferred to keratinocytes where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation as well as progression of melanocytic neoplasia.
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