Gibco™ Human Epigen Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF-homologous portion of the Epigen precursor. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. It is produced in several tissues, including the testis, liver, and heart, as well as in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.

Specifications

• Accession Number: Q6UW88
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 255324
• Molecular Weight (g/mol): 7.9 kDa
• Name: Human Epigen
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: 2310069M11Rik; ALGV3072; EPG; EPGN; epigen; epithelial mitogen; epithelial mitogen homolog; PRO9904; RGD1560084; UNQ3072/PRO9904
• Common Name: Epigen
• Gene Symbol: EPGN
• Biological Activity: Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.