Invitrogen™ Human ERK3 Control Fragment Recombinant Protein

Catalog No.	Quantity
RP108862	100 μL

Catalog No. RP108862 Supplier Invitrogen™ Supplier No. RP108862

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Specifications

• Accession Number: Q16659
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 5597
• Name: Human ERK3 Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 2610021I23Rik; D130053K17Rik; DKFZp686F03189; erk3; ERK-3; Erk-3 related; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; LOC538094 protein; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mapk4; Mapk6; Mapk63; mitogen activated protein kinase 4; mitogen activated protein kinase 6; mitogen-activated protein kinase 6; p55-MAPK; p97mapk; p97-MAPK; Prkm4; Prkm6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; si:ch211-235f12.1
• Common Name: ERK3
• Gene Symbol: MAPK6
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: EDHQELLSVIPVYIRNDMTEPHKPLTQV
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining