Invitrogen™ Human ERRF Synthetic Peptide

Catalog No.	Quantity
PEP1577	50 μg

Catalog No. PEP1577 Supplier Invitrogen™ Supplier No. PEP1577

Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human ERRF2. PEP-1577 can be used as a blocking peptide with polyclonal antibody PA5-34534. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Specifications

• Gene ID (Entrez): 149563
• Species: Human
• Purification Method: purified
• Accession Number: Q8NEQ6
• Common Name: ERRF
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: C1orf64; chromosome 1 open reading frame 64; ER-related factor; ERRF; Gm694; predicted gene 694; RP11-5P18.4; Srarp; SSPR; Steroid receptor-associated and regulated protein; Steroid receptor-regulated protein; uncharacterized protein C1orf64; uncharacterized protein C1orf64 homolog
• Gene Symbol: SRARP
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS