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Invitrogen™ Human Factor V Native Protein

Catalog No. PIRP43126
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Quantity:
50 μg

Description

Native Protein

RP-43126 contains native human Factor V protein. RP-43126 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12259
Concentration 4.8 mg/mL
For Use With (Application) Control
Formulation 50% water with 50% glycerol and no preservative
Gene ID (Entrez) 2153
Molecular Weight (g/mol) 330 kDa
Name Human Factor V
Quantity 50 μg
Source Human
Regulatory Status RUO
Gene Alias Ac2-120; Activated protein C cofactor; AI173222; Cf5; Cf-5; coagulation factor V; coagulation factor V (proaccelerin, labile factor); Coagulation factor V heavy chain; coagulation factor V jinjiang A2 domain; Coagulation factor V light chain; F5; Factor 5; factor V; factor V Leiden; Factor5; FVL; PCCF; Proaccelerin, labile factor; RPRGL1; THPH2
Common Name Factor V
Gene Symbol F5
Conjugate Unconjugated
Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Form Liquid
Protein Subtype Native
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