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Invitrogen™ Human FAM149B1 (aa 379-463) Control Fragment Recombinant Protein

Catalog No. RP97086
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RP97086 100 μL
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Catalog No. RP97086 Supplier Invitrogen™ Supplier No. RP97086
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58953. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. FAM149B1 (Family With Sequence Similarity 149 Member B1) is a Protein Coding gene. Diseases associated with FAM149B1 include Joubert Syndrome 36 and Orofaciodigital Syndrome Vi. An important paralog of this gene is FAM149A. Involved in the localization of proteins to the cilium and cilium assembly. Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96BN6
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 317662
Name Human FAM149B1 (aa 379-463) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias FAM149B1; family with sequence similarity 149 member B1; family with sequence similarity 149, member B1; KIAA0974; Protein FAM149B1; RGD1359592
Common Name FAM149B1
Gene Symbol FAM149B1
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DDKLLMRPGSSTILSTRNWPNRAVEFSTSSLSYTVQSTRRRNPPPRTLHPISTSHSCAETPRSVEEILRGARVPVAPDSLSSPSP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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