Gibco™ Human FGF-18 Recombinant Protein

Catalog No.	Quantity
PHG0234	25 μg

Catalog No. PHG0234 Supplier Gibco™ Supplier No. PHG0234

Description

Recombinant Protein

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 5 mM Tris, pH 8.0, to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Specifications

• Accession Number: O76093
• For Use With (Application): Bioactivity
• Formulation: 10mM tris with no preservative; pH 8
• Gene ID (Entrez): 8817
• Molecular Weight (g/mol): 21.2 kDa
• Name: Human FGF-18
• pH Range: 8
• Purification Method: Purified
• Quantity: 25 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: D130055P09Rik; FGF; FGF18; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; UNQ420/PRO856; zFGF5
• Common Name: FGF18
• Gene Symbol: Fgf18
• Biological Activity: ED50 ≤ 10 ng/mL; determined by the dose-dependent proliferation of Balb/c 3T3 cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human FGF-18 recombinant protein contains 173 amino acids
• Content And Storage: -20°C
• Activity: ED50 ≤ 10 ng/mL; determined by the dose-dependent proliferation of Balb/c 3T3 cells.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Approved for shipment on Wet or Dry Ice
• Expression System: E. coli
• Protein Family: Growth Factors & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: FGFs (Fibroblast Growth Factors)
• Research Category: Neurobiology, Oncology, Stem Cell Research, Microbiology, Differentiation, Angiogenesis
• Product Line: Gibco
• Purity or Quality Grade: >95% by SDS-PAGE

Safety and Handling

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