Gibco™ Human FGF-acidic (FGF-1) Recombinant Protein

Description

Recombinant Protein

Carrier-Free Reconstitution: Reconstitute to 100 μg/mL with PBS. Aliquot and store in polypropylene vials at-20°C. Avoid repeated freezing and thawing. To avoid loss due to adsorption, prepare dilute solutions in appropriate buffer containing at least 0.1% BSA just prior to use. Do not store in dilute solution.

FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.

Specifications

• Accession Number: P05230
• For Use With (Application): Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 2246
• Name: Human FGF-acidic (FGF-1)
• Purification Method: PAGE
• Quantity: 10 μg
• Gene Alias: acidic eye-derived fibroblast growth factor; acidic eye-derived growth factor II; Acidic fibroblast growth factor; aFGF; beta-endothelial cell growth factor; Dffrx; ECGF; ECGFA; ECGFB; ECGF-beta; EDGF; EDGF II; Endothelial cell growth factor; Endothelial cell growth factor alpha; Endothelial cell growth factor beta; endothelial cell growth factor beta and alpha chains; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; endothelial growth factor; Fam; FGF; FGF1; Fgf-1; FGF1 protein; Fgfa; FGF-alpha; Fibroblast growth factor; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); Fibroblast growth factor 1 (heparin binding); fibroblast growth factor, acidic; GLIO703; HBGF1; HBGF-1; heparin-binding growth factor; Heparin-binding growth factor 1; H-FGF-a; M-FGF-a; Prostatropin; unnamed protein product
• Common Name: FGF1
• Biological Activity: ED50 < 10 ng/mL; determined by the dose-dependent stimulation of BaF3 cells.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Content And Storage: -20°C
• Classification: Carrier-Free
• Shipping Condition: Dry Ice
• Expression System: E. coli
• Protein Family: Growth Factors & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: FGFs (Fibroblast Growth Factors)
• Research Category: Angiogenesis, Oncology
• Purity or Quality Grade: >95% by SDS-PAGE