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Invitrogen™ Human GBL Synthetic Peptide

Catalog No. PEP0245 Shop All Thermo Scientific Products
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PEP0245 50 μg
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Catalog No. PEP0245 Supplier Invitrogen™ Supplier No. PEP0245
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Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the carboxy terminus of human GbL. PEP-0245 can be used as a blocking peptide with polyclonal antibody PA5-20127.

G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 64223
Species Human
Purification Method purified
Accession Number Q9BVC4
Common Name GBL
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias 0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; GBL; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; mLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1
Gene Symbol MLST8
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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