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Medchemexpress LLC human GIP(3-30), amide | 1884226-05-4 | 95.63% | 3297.69 | 1 MG
Supplier: Medchemexpress LLC HYP10138A1MG
Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). It acts as a high-affinity antagonist of the human GIP receptor in vitro. This compound shows potential for anti-obesity and anti-diabetic effects.
- High affinity antagonist of the human GIP receptor in vitro.
- Potential anti-obesity effects.
- Potential anti-diabetic effects.
- Competitively binds to GIP receptor (GIPR).
- Blocks GIP-mediated cAMP accumulation (Ki=16.8 nM).
- Blocks β-arrestin recruitment (Ki for β-arrestin-1/2 recruitment is 10.6 nM and 10.2 nM).
- Inhibits receptor internalization.
- Inhibits GIP mediated insulin secretion and signal transduction in adipocytes.
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