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Medchemexpress LLC Human GIP(3-30), amide TFA | 1884226-05-4 | 95.6% | 3297.69 | 5 MG

Supplier: Medchemexpress LLC HYP10138A5MG
Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide. It is a high affinity antagonist of the human GIP receptor in vitro and has potential anti-obesity and anti-diabetic effects.
- High affinity antagonist of the human GIP receptor in vitro.
- Potential anti-obesity and anti-diabetic effects.
- Competitively binds to GIP receptor (GIPR), blocking GIP-mediated cAMP accumulation (Ki=16.8 nM), β-arrestin recruitment (Ki for β-arrestin-1/2 recruitment is 10.6 nM and 10.2 nM) and receptor internalization.
- Inhibits GIP mediated insulin secretion and signal transduction in adipocytes.
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