Invitrogen™ Human GNAI1/GNAI2 (aa 346-355) Synthetic Peptide

Catalog No.	Quantity
PEP129	50 μg

Catalog No. PEP129 Supplier Invitrogen™ Supplier No. PEP129

Description

Synthetic Peptide

PEP-129 is a 10 amino acid synthetic peptide whose sequences are derived from human G protein alpha inhibitor 1/2 protein. The sequence of this peptide is (amino to carboxy terminus): K (346)-N-N-L-K-D-C-G-L-F (355) This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human G protein alpha inhibitor 1/2, catalog # PA1-1000. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water.

The G protein family of signal transducers includes the alpha, beta, gamma subunits and the effector which are most clearly distinguished by their different alpha chains. The family also includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein of unknown function that is abundantly expressed in brain; and transducin 1 and 2, proteins involved in retinal phototransduction. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane-bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.

Specifications

• Gene ID (Entrez): 2770,2771
• Species: Human
• Purification Method: purified
• Accession Number: P04899, P63096
• Common Name: GNAI1/GNAI2
• Concentration: 0.5 mg/mL
• Content And Storage: -20°C. Avoid freeze-thaw cycles.
• Description: Synthetic Peptide
• Format: Lyophilized
• Formulation: Peptide with no preservative
• For Use With (Application): Control
• Gene Alias: adenylate cyclase-inhibiting G alpha protein; AU046200; BPGTPB; C76432; G alpha inhibitory type 2 (a); G alpha inhibitory type 2 (b); G protein subunit alpha i1; G protein subunit alpha i2; Galphai2; Gi; Gi1 protein alpha subunit; Gia; Gialpha1; GIP; GNAI1; Gnai-1; GNAI1 protein; Gnai2; Gnai-2; GNAI2B; GTP-binding protein (G-alpha-i2); GTP-binding regulatory protein Gi alpha-2 chain; guanidine nucleotide binding protein, (G protein) , alpha inhibiting activity polypeptide 2; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting 2; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide binding protein, alpha inhibiting 1; guanine nucleotide binding protein, alpha inhibiting 2; guanine nucleotide binding protein, alpha inhibiting activity polypeptide 2; guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i), alpha-1 subunit; guanine nucleotide-binding protein G(i), alpha-2 subunit; H_LUCA15.1; H_LUCA16.1; inhibitory GTP-binding protein subunit alpha 2; p-alpha-h subunit; unnamed protein product
• Gene Symbol: GNAI1, GNAI2
• Lyophilized: Yes
• Preservative: No preservative
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Sequence: K(346)-N-N-L-K-D-C-G-L-F(355)