Invitrogen™ Human HAX1 beta Synthetic Peptide

Catalog No.	Quantity
PEP0770	50 μg

Catalog No. PEP0770 Supplier Invitrogen™ Supplier No. PEP0770

Description

Synthetic Peptide

This peptide corresponds to 10 amino acids near the amino terminus of human Hax1 isoform b. PEP-0770 can be used as a blocking peptide with polyclonal antibody PA5-20650.

The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.

Specifications

• Gene ID (Entrez): 10456
• Species: Human
• Purification Method: purified
• Accession Number: O00165
• Common Name: HAX1b
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: Hax1; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1 associated protein X-1; HCLS1 associated X-1; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1; HS1-binding protein 1; Hs1bp1; HSP1BP-1; mHAX-1s; RP11-137P24.1; SCN3; SIG-111; Silg111
• Gene Symbol: HAX1
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS