Gibco™ Human HPRG Recombinant Protein, PeproTech®

Catalog No.	Quantity
100-60-5UG	5 μg
10060100UG	100 μg
100-60-1MG	1 mg
10060250UG	250 μg
100-60-25UG	25 μg
10060500UG	500 μg

Catalog No. 100-60-5UG Supplier Gibco™ Supplier No. 100605UG

Description

Recombinant Protein

Recombinant Human HPRG is a 57.7 kDa glycoprotein containing 507 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Specifications

• Accession Number: P04196
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 3273
• Molecular Weight (g/mol): 57.7 kDa
• Name: Human HPRG
• Quantity: 5 μg
• Source: CHO cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: AI265597; AW413091; D16jh2; D18020; DKFZp779H1622; histidine rich glycoprotein; histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG; HRG1; Hrgp; THPH11
• Common Name: HRG
• Gene Symbol: HRG
• Biological Activity: Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface. The ED50 for this effect is 1.5-2.0 ug/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: VSPTDCSAVE PEAEKALDLI NKRRRDGYLF QLLRIADAHL DRVENTTVYY LVLDVQESDC SVLSRKYWND CEPPDSRRPS EIVIGQCKVI ATRHSHESQD LRVIDFNCTT SSVSSALANT KDSPVLIDFF EDTERYRKQA NKALEKYKEE NDDFASFRVD RIERVARVRG GEGTGYFVDF SVRNCPRHHF PRHPNVFGFC RADLFYDVEA LDLESPKNLV INCEVFDPQE HENINGVPPH LGHPFHWGGH ERSSTTKPPF KPHGSRDHHH PHKPHEHGPP PPPDERDHSH GPPLPQGPPP LLPMSCSSCQ HATFGTNGAQ RHSHNNNSSD LHPHKHHSHE QHPHGHHPHA HHPHEHDTHR QHPHGHHPHG HHPHGHHPHG HHPHGHHPHC HDFQDYGPCD PPPHNQGHCC HGHGPPPGHL RRRGPGKGPR PFHCRQIGSV YRLPPLRKGE VLPLPEANFP SFPLPHHKHP LKPDNQPFPQ SVSESCPGKF KSGFPQVSMF FTHTFPK
• Content And Storage: -20°C
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.